Transfer Factor Plus combines Tri-Factor Formula with zinc and a proprietary mushroom blend. The core ingredient system is derived from cow colostrum and chicken egg yolk, while the additional blend currently features shiitake, maitake, agaricus, and cordyceps.
The complete current label should be checked before purchase because formulas and other ingredients can change.
Ingredient map
| Ingredient group | Why it is present |
|---|---|
| UltraFactor | 4Life proprietary cow-colostrum-derived component |
| OvoFactor | 4Life proprietary chicken-egg-yolk-derived component |
| NanoFactor | Proprietary small-molecule fraction |
| Zinc | Essential mineral supporting normal immune function |
| Shiitake | Mushroom ingredient |
| Maitake | Mushroom ingredient |
| Agaricus | Mushroom ingredient |
| Cordyceps | Mushroom ingredient |
| Other ingredients | Capsule and manufacturing components listed on the label |
Tri-Factor Formula
Tri-Factor Formula is 4Life’s proprietary framework built around UltraFactor, OvoFactor, and NanoFactor.
These names are brand-specific. They should not be presented as universal scientific classifications used across immunology.
UltraFactor
4Life associates UltraFactor with cow colostrum.
Colostrum contains many proteins and peptides, but a proprietary fraction should not be treated as equivalent to ordinary whole-colostrum powder.
OvoFactor
OvoFactor is associated with chicken egg yolk.
This is important for consumers with egg allergy. The label—not assumptions about purification—controls the allergen decision.
NanoFactor
4Life describes NanoFactor as mini molecules or a small-molecule component.
The name does not by itself establish greater absorption, superior potency, or a specific clinical effect.
Zinc
Zinc is a defined essential nutrient. It supports normal immune-cell production and function.
The zinc amount should be evaluated alongside all other zinc sources. Excessive long-term intake can interfere with copper and cause adverse effects.
Shiitake
Shiitake contains polysaccharides and other compounds studied in nutrition and immune research.
The relevance of any study depends on extract type, dose, and endpoint.
Maitake
Maitake is another mushroom used in wellness formulas. Product-specific evidence is more relevant than general claims about the species.
Agaricus
Agaricus species have been studied in laboratory and human contexts, but evidence varies widely by preparation.
The word “agaricus” does not identify one standardized extract.
Cordyceps
Cordyceps is used in traditional and modern supplement formulations.
Different products may use different species, cultivated material, extracts, or mycelial preparations.
Proprietary blend limitations
A proprietary blend may identify its components without disclosing each individual amount.
This can make it harder to compare:
- dose;
- standardization;
- active constituents;
- research relevance;
- value.
Consumers should avoid assuming that the longest ingredient list is automatically the strongest product.
Other ingredients
Capsules and manufacturing ingredients may include stabilizers, flow agents, or capsule materials.
These matter for:
- dietary preferences;
- sensitivities;
- swallowing;
- storage;
- product comparison.
Milk and egg allergens
Plus uses cow-colostrum- and egg-yolk-derived material.
A serious milk or egg allergy requires direct label verification and appropriate guidance.
Ingredient evidence vs product evidence
Research on zinc, shiitake, or colostrum is not automatically evidence for Transfer Factor Plus.
The strongest product claim requires evidence on the finished formula at the labeled serving.
Bottom line
Transfer Factor Plus is a multi-ingredient formula. Its main differentiators are Tri-Factor Formula, zinc, and four mushroom ingredients.
A responsible evaluation separates each ingredient’s role, total intake, allergen source, dose transparency, and product-specific evidence.
Related guides
- Transfer Factor Plus product guide
- Transfer Factor Plus vs Tri-Factor
- Tri-Factor ingredients
- Transfer Factor allergens
- Immune ingredient guide
Sources
- https://www.4life.com/corp/product/transfer-factor-plus-tri-factor/89
- https://www.4life.com/corp/page/45/transfer-factor-core-2
- https://ods.od.nih.gov/factsheets/Zinc-Consumer/
- https://www.fda.gov/food/food-labeling-nutrition/food-allergies
Important disclosure
Immune4Life is an independent 4Life Affiliate education website, not the 4Life corporate website. Some links may open an official personalized 4Life MyShop and may result in affiliate credit. Product formulas, labels, directions, availability, and program terms can change. Verify the current U.S. product label and official 4Life listing before ordering.
These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. This article is educational and is not individualized medical advice.

